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Goji Berries: Which Benefits Do They Really Have?

Plus: these different kinds of knee pain mean very different things

Today’s almonds have been activated by:

“Everything in moderation” is unfortunate advice. Some things in moderation will kill us immediately!

Other things in moderation will merely make us moderately more likely to suffer heart disease, cancer, etc.

We all may choose unhealthy things from time to time, but it’s good to at least make that choice mindfully when we do—lest it become a moderately bad habit!

One almond
IN A RUSH?

Today’s 30-Second Summary

If you don’t have time to read the whole email today, here are some key takeaways:

  • Goji berries are punchy little things with a lot of benefits. They’re packed full of phytochemicals including helpful polysaccharides, carotenoids, phenolic acids, and flavonoids.

    • Importantly, this means they’re good against oxidative stress (a major factor in cellular aging), against cancer (we discuss five kinds, but it probably goes for the rest), and are (probably; see main feature) also immunomodulatory (in a good way).

    • They also do help against age-related macular degeneration!

  • Being unable to easily participate in spoken conversations is not just an inconvenience; it’s also a [causal, fixable] risk factor for age-related cognitive decline.

    • Today’s sponsor, Hear.com, are offering the most cutting-edge dual-processing technology in hearing aids that isolate and separate speech from background noise.

Read on to learn about these things and more…

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👀 WATCH AND LEARN

My knee hurts here! 10 typical pain spots and what they mean (6:55)

Different knee pains mean different things, and knowing can make a difference:

The ten spots:

  • 0:40 | Patellofemoral pain syndrome

  • 1:45 | Meniscus pain

  • 2:19 | Patellar tendinitis

  • 2:41 | Osgood-Schlatter

  • 3:04 | ITB friction syndrome

  • 3:25 | Quadriceps tendinitis

  • 3:53 | Plica syndrome

  • 4:23 | Pes anserinus tendinitis

  • 4:57 | Hoffa syndrome

  • 5:41 | Tibiofibular joint pain

Want to watch it, but not right now? Bookmark it for later 🔖

💊 MAIN FEATURE

Are Goji Berries Really A Superfood?

Goji berries are popularly considered a superfood, and sold for everything from anti-aging effects, to exciting benefits* that would get this email directed to your spam folder if we described them.

*We searched so you don’t have to: there doesn’t seem to be much research to back [that claim that we can’t mention], but we did find one paper on its “invigorating” benefits for elderly male rats. We prefer to stick to human studies where we can!

So how does the science stack up for the more mainstream claims?

Antioxidant effects

First and most obvious for this fruit that’s full of helpful polysaccharides, carotenoids, phenolic acids, and flavonoids, yes, they really do have strong antioxidant properties:

Immune benefits

Things that are antioxidant are generally also anti-inflammatory, and often have knock-on benefits for the immune system. That appears to be the case here.

For example, in this small-but-statistically-significant study (n=60) in healthy adults (aged 55–72 years)

❝The GoChi group showed a statistically significant increase in the number of lymphocytes and levels of interleukin-2 and immunoglobulin G compared to pre-intervention and the placebo group, whereas the number of CD4, CD8, and natural killer cells or levels of interleukin-4 and immunoglobulin A were not significantly altered. The placebo group showed no significant changes in any immune measures.

Whereas the GoChi group showed a significant increase in general feelings of well-being, such as fatigue and sleep, and showed a tendency for increased short-term memory and focus between pre- and post-intervention, the placebo group showed no significant positive changes in these measures.❞

“GoChi” here is a brand name for goji berries, and it’s not clear from the abstract whether the company funded the study:

Here’s another study, this time n=150, and ages 65–70 years old. This time it’s with a different brand (“Lacto-Wolfberry”, a milk-with-goji supplement drink) and it’s also unclear whether the company funded the study. However, taking the data at face value:

❝In conclusion, long-term dietary supplementation with Lacto-Wolfberry in elderly subjects enhances their capacity to respond to antigenic challenge without overaffecting their immune system, supporting a contribution to reinforcing immune defense in this population. ❞

In other words: it allowed those who took it to get measurably more benefit from the flu vaccinations that they received, without any ill effects.

Anticancer potential

This one’s less contentious (the immune benefits seemed very credible; we’d just like to see more transparent research to say for sure), so in the more clearly-evidenced case against cancer we’ll just drop a few quick studies, clipped for brevity:

You get the idea: it helps!

Bonus benefit for the eyes

Goji berries also help against age-related macular degeneration. The research for this is in large part secondary, i.e. goji berries contain things x, y, and z, and then separate studies say that those things help against age-related macular degeneration.

We did find some goji-specific studies though! One of them was for our old friends the “Lacto-Wolfberry” people and again, wasn’t very transparent, so we’ll not take up extra time/space with that one here.

Instead, here’s a much clearer, transparent, and well-referenced study with no conflicts of interest, that found:

❝Overall, daily supplementation with Goji berry for 90d improves MPOD by increasing serum Z levels rather than serum L levels in early AMD patients. Goji berry may be an effective therapeutic intervention for preventing the progression of early AMD.❞

  • MPOD = Macular Pigment Optical Density, a standard diagnostic tool for age-related macular degeneration

  • AMD = Age-related Macular Degeneration

(that whole paper is very compelling reading, if you have time)

If you want a quicker read, we offer:

and also…

Where to get goji berries?

You can probably find them at your local health food store, if not the supermarket. However, if you’d like to buy them online, here’s an example product on Amazon for your convenience 😎

Enjoy!

❤️ OUR SPONSORS MAKE THIS PUBLICATION POSSIBLE

German engineering at its finest.

In a groundbreaking development, German entrepreneurs Dr. Marco Vietor and Paul Crusius have unveiled a virtually invisible hearing aid that is taking the US by storm.

It’s called Horizon by hear.com. Bluetooth-enabled, audiologist-backed, and smaller than a coffee bean.

Please do visit our sponsors—they help keep 10almonds free

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🤫 A WORD TO THE WISE

Dr. Greger’s Anti-Aging Eight

We read his latest (very dense and long) book so you don’t have to! We still recommend it, but meanwhile, you can check out his top 8 anti-aging interventions here:

📖 ONE-MINUTE BOOK REVIEW

On This Bright Day: A Year of Reflections for Lasting Food Freedom – by Dr. Susan Thompson

This book is principally aimed at those who have struggled with emotional/comfort eating, over-eating, and/or compulsive eating of some kind.

However, its advices go for the "little compulsions" too, the many small unhealthy choices that add up. Thus, this book has value for most if not all of us.

The format is: each day has a little quotation, followed by a short discussion of that, which is then underlined by an affirmation for the day.

The main thrust of the book is to promote mindful eating, and it does this well with daily reminders that are helpful without being preachy.

Bottom line: if you enjoy "daily reader" type books and would like a daily reminder to practice mindful eating, then this book is for you!

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Wishing you the most well-informed start to the week,

The 10almonds Team