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How Acetaminophen Suppresses Endocannabinoids
Plus: what you need to understand about your body‚ to lose belly fat
The 10almonds Team
May 17, 2025
Happy weekend 👋
Problem, or opportunity? Try reframing “I have to…” into “I get to…”, for more energy to Do The Thing(s)™
In today’s email we cover acetaminophen/paracetamol (Tylenol et al.), losing belly fat, and how to enjoy a low-insulin lifestyle.
Would you pay thousands of dollars for clear hearing? The good news is, you don’t have to, because modern hearing aids simply don’t cost that much to make. Today’s sponsor Oricle is offering state-of-the-art hearing aids for just $99, no doctor visits needed. They have a modern, virtually invisible design, they have a long-lasting USB-C rechargeable battery, noise cancellation, and everything else you might reasonably expect of hearing aids: check them out, here!
Today’s Main Feature
 | How Acetaminophen Suppresses Endocannabinoids…contrary to all expectations (and how this can lead to more effective acetaminophen-like pain relief, without the toxicity): |
Recommended Reading
 | What You Should Know About Bipolar DisorderBipolar disorder is very poorly understood by most people, so here’s what it’s actually like: |
 | Daily Activity Levels & The Measurable Difference They Make To Brain Health…including in the short term (cognitive performance improvements within hours of even moderate activity) as well as the long: |
Watch and Learn
“Give Me 6 Minutes... I'll Save You 10 Years Of Trying To Lose Belly Fat!”
Cutting calories is not the answer. Understanding your body, however, is:
Prefer text? The above video will take you to a 10almonds page with a text overview, as well as the video!
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Please do visit our sponsors—they help keep 10almonds free
This Or That?
Vote on Which is Healthier
Yesterday we asked you to choose between pear and watermelon—we picked the pear (click here to read about why), as did 48% of you!
Now for today’s choice:
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Click on whichever you think is better for you!
Bonus (Sponsored) Recommendation
We know 10almonds readers love learning in a convenient, bite-size fashion. Check out this list of other newsletters our readers also enjoy!
One-Minute Book Review
Low Insulin Lifestyle: My personal journey with PCOS and the science behind a low insulin lifestyle – by Dr. Ali Chappell
The author, a registered dietician (RD) and PhD nutritionist, talks about her successful approach for managing her PCOS with diet—and unlike many books or articles about such, her emphasis is not on phytoestrogens, but rather, on insulin management.
Why? Because PCOS and insulin resistance are strongly linked, insofar as each promotes the other. Since it is difficult to directly tackle PCOS (whose cause is not known and whose pathology is hazily understood at best), she opts for tackling this strongly-linked comorbidity, insulin resistance, as it is much better understood and much easier to directly affect. And then, by reducing insulin resistance, PCOS symptoms are simultaneously alleviated.
She starts by explaining the science of PCOS so far as it is understood—so, mostly the risk factors and the symptoms—and then, extensively, the science of insulin resistance (especially its causes, its consequences, and how to reverse it).
The “how to reverse it” part is of course the greatest value of the book, and focuses on avoiding insulin triggers. Notably, it also covers well-established insulin triggers that don’t necessarily cause blood sugar spikes and so can often go unnoticed outside of the lab. While blood sugar levels are often used as a proxy for measuring insulin, it’s not a 1:1 relationship, so simply avoiding blood sugar spikes (while still helpful) would not by itself eliminate insulin spikes. Thus, the extra information of this book being useful.
The style is varied; we see clear and comprehensible textbook-style clinical explanations, anecdotes about case studies, and a wealth of actual research, with citations linking to such throughout, along with direct practical advice of the “so do this and this” kind.
Bottom line: if you or a loved one have PCOS or a similar condition (large overlap with many untreated menopause symptoms, of course), then this book can help you while—as a bonus—vastly improving your systemic health too (since insulin affects many other things).
Penny For Your Thoughts?
What did you think of today's newsletter?We always love to hear from you, whether you leave us a comment or even just a click in the poll if you're speeding by! |
Wishing you a wonderfully restorative weekend,
The 10almonds Team
